6C8E

RNA-imidazolium-bridged intermediate complex, 4h soaking

Summary for 6C8E

• Entry DOI: 10.2210/pdb6c8e/pdb
• Descriptor: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), 2-amino-1-[(R)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-3-[(S)-{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium (3 entities in total)
• Functional Keywords: rna, intermediate, dinucleotide
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 10574.63

Authors

Zhang, W.,Szostak, J.W. (deposition date: 2018-01-24, release date: 2018-05-30, Last modification date: 2024-05-01)

• Primary citation: Zhang, W.,Walton, T.,Li, L.,Szostak, J.W.; Crystallographic observation of nonenzymatic RNA primer extension.; Elife, 7:-, 2018; PubMed: 29851379; DOI: 10.7554/eLife.36422

Experimental method

X-RAY DIFFRACTION (1.8 Å)