6C7O

Crystal structure of D477G ACO/RPE65 chimera, trigonal crystal form

Summary for 6C7O

• Entry DOI: 10.2210/pdb6c7o/pdb
• Descriptor: Apocarotenoid-15,15'-oxygenase, FE (II) ION (3 entities in total)
• Functional Keywords: non-heme iron, chimera, 7-bladed propeller, dominant mutation, oxidoreductase
• Biological source: Synechocystis sp. (strain PCC 6803 / Kazusa)
• Total number of polymer chains: 2
• Total formula weight: 108914.38

Authors

Kiser, P.D.,Shi, W. (deposition date: 2018-01-23, release date: 2018-04-25, Last modification date: 2023-10-04)

• Primary citation: Choi, E.H.,Suh, S.,Sander, C.L.,Hernandez, C.J.O.,Bulman, E.R.,Khadka, N.,Dong, Z.,Shi, W.,Palczewski, K.,Kiser, P.D.; Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.; Hum.Mol.Genet., 27:2225-2243, 2018; PubMed: 29659842; DOI: 10.1093/hmg/ddy128

Experimental method

X-RAY DIFFRACTION (3.15 Å)