6C5X
Crystal Structure of SOCS1 in complex with ElonginB and ElonginC
Summary for 6C5X
Entry DOI | 10.2210/pdb6c5x/pdb |
Descriptor | Elongin-B, Elongin-C, Suppressor of Cytokine Signalling 1, ... (5 entities in total) |
Functional Keywords | complex, ubiquitination, cytokine signalling, socs, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q15370 Q15369 |
Total number of polymer chains | 7 |
Total formula weight | 87127.09 |
Authors | Kershaw, N.J.,Laktyushin, A.,Babon, J.J. (deposition date: 2018-01-17, release date: 2018-05-02, Last modification date: 2023-11-15) |
Primary citation | Liau, N.P.D.,Laktyushin, A.,Lucet, I.S.,Murphy, J.M.,Yao, S.,Whitlock, E.,Callaghan, K.,Nicola, N.A.,Kershaw, N.J.,Babon, J.J. The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun, 9:1558-1558, 2018 Cited by PubMed: 29674694DOI: 10.1038/s41467-018-04013-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.105 Å) |
Structure validation
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