6C5U

Aminoglycoside Phosphotransferase (2'')-Ia in complex with GMPPNP, Magnesium, and Ribostamycin, Alternate form

Summary for 6C5U

Entry DOI	10.2210/pdb6c5u/pdb
Descriptor	Bifunctional AAC/APH, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RIBOSTAMYCIN, ... (6 entities in total)
Functional Keywords	kinase, antibiotic, aminoglycoside, resistance, transferase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Staphylococcus aureus
Total number of polymer chains	4
Total formula weight	147545.80
Authors	Caldwell, S.J.,Berghuis, A.M. (deposition date: 2018-01-16, release date: 2018-04-11, Last modification date: 2023-10-04)
Primary citation	Caldwell, S.J.,Berghuis, A.M. Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia. Antimicrob. Agents Chemother., 62:-, 2018 Cited by PubMed: 29661878 DOI: 10.1128/AAC.00202-18 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation