6C09
Ternary crystal structure of the 3C8 TCR-CD1c-monoacylglycerol complex
Summary for 6C09
Entry DOI | 10.2210/pdb6c09/pdb |
Descriptor | T-cell surface glycoprotein CD1c, DI(HYDROXYETHYL)ETHER, Beta-2-microglobulin, ... (11 entities in total) |
Functional Keywords | t cell receptor, antigen presentation, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 96710.37 |
Authors | Wun, K.S.,Rossjohn, J. (deposition date: 2017-12-28, release date: 2018-03-21, Last modification date: 2023-10-04) |
Primary citation | Wun, K.S.,Reijneveld, J.F.,Cheng, T.Y.,Ladell, K.,Uldrich, A.P.,Le Nours, J.,Miners, K.L.,McLaren, J.E.,Grant, E.J.,Haigh, O.L.,Watkins, T.S.,Suliman, S.,Iwany, S.,Jimenez, J.,Calderon, R.,Tamara, K.L.,Leon, S.R.,Murray, M.B.,Mayfield, J.A.,Altman, J.D.,Purcell, A.W.,Miles, J.J.,Godfrey, D.I.,Gras, S.,Price, D.A.,Van Rhijn, I.,Moody, D.B.,Rossjohn, J. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat. Immunol., 19:397-406, 2018 Cited by PubMed: 29531339DOI: 10.1038/s41590-018-0065-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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