6BYU

X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex

Summary for 6BYU

Entry DOI	10.2210/pdb6byu/pdb
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	rna polymerase, ppapp, escherichia coli x-ray structure, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Escherichia coli More
Total number of polymer chains	12
Total formula weight	921340.18
Authors	Murakami, K.S.,Molodtsov, V. (deposition date: 2017-12-21, release date: 2018-01-17, Last modification date: 2023-10-04)
Primary citation	Bruhn-Olszewska, B.,Molodtsov, V.,Sobala, M.,Dylewski, M.,Murakami, K.S.,Cashel, M.,Potrykus, K. Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochim. Biophys. Acta, 1861:731-742, 2018 Cited by PubMed: 30012465 DOI: 10.1016/j.bbagrm.2018.07.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation