6BXC

Crystal structure of N-terminal fragment of Zebrafish Toll-Like Receptor 5 (TLR5) with Lamprey Variable Lymphocyte Receptor 9 (VLR9) bound

Summary for 6BXC

Entry DOI	10.2210/pdb6bxc/pdb
Descriptor	Toll-like receptor 5b, Variable lymphocyte receptor B chimera, Variable Lymphocyte Receptor 9 (VLR9), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	vlr, leucine-rich repeat, antibody, immune system
Biological source	Danio rerio (Zebrafish) More
Total number of polymer chains	4
Total formula weight	142063.84
Authors	Gunn, R.J.,Wilson, I.A.,Cooper, M.D.,Herrin, B.R. (deposition date: 2017-12-18, release date: 2018-05-09, Last modification date: 2023-10-04)
Primary citation	Gunn, R.J.,Herrin, B.R.,Acharya, S.,Cooper, M.D.,Wilson, I.A. VLR Recognition of TLR5 Expands the Molecular Characterization of Protein Antigen Binding by Non-Ig-based Antibodies. J. Mol. Biol., 430:1350-1367, 2018 Cited by PubMed: 29596914 DOI: 10.1016/j.jmb.2018.03.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation