6BSR

Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the benzylpenicillin bound form.

Summary for 6BSR

• Entry DOI: 10.2210/pdb6bsr/pdb
• Related: 6BSQ
• Descriptor: PBP4 protein, GLYCEROL, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: penicillin binding protein, transpeptidase, beta-lactam, antibiotic, hydrolase, benzylpenicillin
• Biological source: Enterococcus faecalis (Streptococcus faecalis)
• Total number of polymer chains: 1
• Total formula weight: 73939.49

Authors

Moon, T.M.,D'Andrea, E.D.,Peti, W.,Page, R. (deposition date: 2017-12-04, release date: 2018-10-31, Last modification date: 2024-03-13)

• Primary citation: Moon, T.M.,D'Andrea, E.D.,Lee, C.W.,Soares, A.,Jakoncic, J.,Desbonnet, C.,Garcia-Solache, M.,Rice, L.B.,Page, R.,Peti, W.; The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.; J. Biol. Chem., 293:18574-18584, 2018; PubMed: 30355734; DOI: 10.1074/jbc.RA118.006052

Experimental method

X-RAY DIFFRACTION (2.34 Å)