6BMD

RNA hairpin containing GpppG-oligo to mimic intermediate formed by activated monomer and activated downstream helper

Summary for 6BMD

• Entry DOI: 10.2210/pdb6bmd/pdb
• Descriptor: RNA (5'-R(P*GP*AP*GP*GP*UP*GP*(LCC)P*(LCC)P*GP*AP*GP*CP*GP*CP*GP*AP*AP*AP*GP*CP*GP*CP*UP*C)-3'), RNA (5'-D(*(GP3))-R(P*CP*AP*CP*CP*UP*CP*A)-3') (3 entities in total)
• Functional Keywords: rna, gpppg, helper, intermediate
• Biological source: synthetic construct; More
• Total number of polymer chains: 6
• Total formula weight: 32293.64

Authors

Zhang, W.,Szostak, J.W. (deposition date: 2017-11-14, release date: 2018-02-21, Last modification date: 2023-10-04)

• Primary citation: Zhang, W.,Tam, C.P.,Zhou, L.,Oh, S.S.,Wang, J.,Szostak, J.W.; Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.; J. Am. Chem. Soc., 140:2829-2840, 2018; PubMed: 29411978; DOI: 10.1021/jacs.7b11750

Experimental method

X-RAY DIFFRACTION (3 Å)