6BM8

Crystal structure of glycoprotein B from Herpes Simplex Virus type I

Summary for 6BM8

• Entry DOI: 10.2210/pdb6bm8/pdb
• Related: 5V2S
• Descriptor: Envelope glycoprotein B, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: viral protein, fusogen, bitopic membrane protein
• Biological source: Human herpesvirus 1 (HHV-1)
• Total number of polymer chains: 1
• Total formula weight: 94981.80

Authors

Cooper, R.S.,Heldwein, E.E. (deposition date: 2017-11-13, release date: 2018-05-16, Last modification date: 2023-10-04)

• Primary citation: Cooper, R.S.,Georgieva, E.R.,Borbat, P.P.,Freed, J.H.,Heldwein, E.E.; Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB.; Nat. Struct. Mol. Biol., 25:416-424, 2018; PubMed: 29728654; DOI: 10.1038/s41594-018-0060-6

Experimental method

X-RAY DIFFRACTION (4.1 Å)