6BCB
A Complex between PH Domain of p114RhoGEF and Activated RhoA Bound to a GTP Analog
Summary for 6BCB
| Entry DOI | 10.2210/pdb6bcb/pdb |
| Descriptor | Transforming protein RhoA, Rho guanine nucleotide exchange factor 18, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (6 entities in total) |
| Functional Keywords | rho gtpase guanine nucleotide exchange factors rhogef pleckstrin homology ph domain, signaling protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 38272.02 |
| Authors | Sternweis, P.C.,Chen, Z. (deposition date: 2017-10-20, release date: 2017-12-13, Last modification date: 2024-03-13) |
| Primary citation | Chen, Z.,Gutowski, S.,Sternweis, P.C. Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase. Data Brief, 17:356-362, 2018 Cited by PubMed: 29876405DOI: 10.1016/j.dib.2018.01.024 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.401 Å) |
Structure validation
Download full validation report
