6B5Q

DCN1 bound to 38

Summary for 6B5Q

Entry DOI	10.2210/pdb6b5q/pdb
Related PRD ID	PRD_002285
Descriptor	DCN1-like protein 1, Peptidomimetic Inhibitors DI-591, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	e3 ligase, complex, ligase-inhibitor complex, ligase, ligase/inhibitor
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : Q96GG9
Total number of polymer chains	4
Total formula weight	54254.76
Authors	Stuckey, J. (deposition date: 2017-09-29, release date: 2018-02-28, Last modification date: 2023-11-15)
Primary citation	Zhou, H.,Zhou, W.,Zhou, B.,Liu, L.,Chern, T.R.,Chinnaswamy, K.,Lu, J.,Bernard, D.,Yang, C.Y.,Li, S.,Wang, M.,Stuckey, J.,Sun, Y.,Wang, S. High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein-Protein Interaction. J. Med. Chem., 61:1934-1950, 2018 Cited by PubMed: 29438612 DOI: 10.1021/acs.jmedchem.7b01455 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation