6AZZ
Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190
Summary for 6AZZ
Entry DOI | 10.2210/pdb6azz/pdb |
Descriptor | 1190 antibody, heavy chain, 1190 antibody, light chain, Pfs25, ... (6 entities in total) |
Functional Keywords | transmission blocking vaccine, malaria, antibody, egf-like domain, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 135067.67 |
Authors | Scally, S.W.,McLeod, B.,Bosch, A.,King, C.R.,Julien, J.P. (deposition date: 2017-09-13, release date: 2017-11-08, Last modification date: 2023-10-04) |
Primary citation | Scally, S.W.,McLeod, B.,Bosch, A.,Miura, K.,Liang, Q.,Carroll, S.,Reponen, S.,Nguyen, N.,Giladi, E.,Ramisch, S.,Yusibov, V.,Bradley, A.,Lemiale, F.,Schief, W.R.,Emerling, D.,Kellam, P.,King, C.R.,Julien, J.P. Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8:1568-1568, 2017 Cited by PubMed: 29146922DOI: 10.1038/s41467-017-01924-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report