6AVN
Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A
Summary for 6AVN
Entry DOI | 10.2210/pdb6avn/pdb |
Descriptor | PGV19 Fab heavy chain, PGV19 Fab light chain, GLYCEROL, ... (5 entities in total) |
Functional Keywords | vrc01-class lambda antibody, cd4 binding site epitope, immune system, anti-hiv neutralizing antibody |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 47072.75 |
Authors | Sarkar, A.,Wilson, I.A. (deposition date: 2017-09-03, release date: 2018-06-27, Last modification date: 2023-10-04) |
Primary citation | Sarkar, A.,Bale, S.,Behrens, A.J.,Kumar, S.,Sharma, S.K.,de Val, N.,Pallesen, J.,Irimia, A.,Diwanji, D.C.,Stanfield, R.L.,Ward, A.B.,Crispin, M.,Wyatt, R.T.,Wilson, I.A. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nat Commun, 9:1956-1956, 2018 Cited by PubMed: 29769533DOI: 10.1038/s41467-018-04272-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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