6ASE

KRAS mutant-A59G in GDP-bound

Summary for 6ASE

• Entry DOI: 10.2210/pdb6ase/pdb
• Related: 6ASA
• Descriptor: GTPase KRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: kras mutant a59g-gdp state, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01116
• Total number of polymer chains: 1
• Total formula weight: 19782.29

Authors

Westover, K.,Lu, J. (deposition date: 2017-08-24, release date: 2018-01-24, Last modification date: 2023-10-04)

• Primary citation: Lu, J.,Bera, A.K.,Gondi, S.,Westover, K.D.; KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.; Biochemistry, 57:324-333, 2018; PubMed: 29235861; DOI: 10.1021/acs.biochem.7b00974

Experimental method

X-RAY DIFFRACTION (1.554 Å)