6AA3
Crystal structure of MTH1 in apo form (cocktail No. 1)
Summary for 6AA3
Entry DOI | 10.2210/pdb6aa3/pdb |
Descriptor | 7,8-dihydro-8-oxoguanine triphosphatase, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | hydrolase, nudt1, antitumor protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19277.85 |
Authors | Yokoyama, T.,Kitakami, R.,Mizuguchi, M. (deposition date: 2018-07-17, release date: 2019-03-06, Last modification date: 2023-11-22) |
Primary citation | Yokoyama, T.,Kitakami, R.,Mizuguchi, M. Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening. Eur J Med Chem, 167:153-160, 2019 Cited by PubMed: 30771603DOI: 10.1016/j.ejmech.2019.02.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.001 Å) |
Structure validation
Download full validation report