5ZI0
Ketoreductase LbCR mutant - M8
Summary for 5ZI0
Entry DOI | 10.2210/pdb5zi0/pdb |
Descriptor | 3-oxoacyl-acyl carrier protein reductase (2 entities in total) |
Functional Keywords | ketoreductase, short-chain dehydrogenase/reductase (sdr), oxidoreductase |
Biological source | Lactobacillus brevis (strain ATCC 367 / JCM 1170) |
Total number of polymer chains | 4 |
Total formula weight | 118269.93 |
Authors | Gong, X.M.,Zheng, G.W.,Xu, J.H. (deposition date: 2018-03-14, release date: 2019-01-16, Last modification date: 2024-03-27) |
Primary citation | Gong, X.M.,Zhen, Q.,Li, F.L.,Zeng, B.B.,Zheng, G.W.,Xu, J.H. Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor Acs Catalysis, 9:147-153, 2019 Cited by DOI: 10.1021/acscatal.8b03382PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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