5ZEJ

Crystal structure of the bacterial A1408me1A-mutant ribosomal decoding site in complex with paromomycin

Replaces:  4WCR

Summary for 5ZEJ

• Entry DOI: 10.2210/pdb5zej/pdb
• Related: 5ZEG 5ZEI
• Descriptor: RNA (5'-R(P*UP*GP*CP*GP*UP*CP*(1MA)P*CP*GP*UP*CP*GP*AP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3'), PAROMOMYCIN (3 entities in total)
• Functional Keywords: ribosome, rna, aminoglycoside, antibiotic-resistance
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 14742.17

Authors

Kanazawa, H.,Baba, F.,Koganei, M.,Kondo, J. (deposition date: 2018-02-27, release date: 2018-03-21, Last modification date: 2023-11-22)

• Primary citation: Kanazawa, H.,Baba, F.,Koganei, M.,Kondo, J.; A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.; Nucleic Acids Res., 45:12529-12535, 2017; PubMed: 29036479; DOI: 10.1093/nar/gkx882

Experimental method

X-RAY DIFFRACTION (3.5 Å)