5Z98

Crystal Structure of the Primate APOBEC3H Dimer mediated by RNA Duplex

Summary for 5Z98

• Entry DOI: 10.2210/pdb5z98/pdb
• Descriptor: Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like protein 3H, RNA (5'-R(P*CP*UP*GP*CP*CP*GP*GP*GP*UP*A)-3'), RNA (5'-R(*AP*UP*AP*CP*CP*CP*GP*GP*CP*A)-3'), ... (5 entities in total)
• Functional Keywords: apobec3, apobec3h, cytidine deaminase, deaminase, anti-hiv, vif, dsrna, cancer, hiv-1, siv, chimpanzee, dimerization, pan troglodytes, antiviral protein-rna complex, antiviral protein/rna
• Biological source: Pan troglodytes (Chimpanzee); More
• Total number of polymer chains: 4
• Total formula weight: 50308.35

Authors

Matsuoka, T.,Nagae, T.,Ode, H.,Watanabe, N.,Iwatani, Y. (deposition date: 2018-02-02, release date: 2018-08-15, Last modification date: 2023-11-22)

• Primary citation: Matsuoka, T.,Nagae, T.,Ode, H.,Awazu, H.,Kurosawa, T.,Hamano, A.,Matsuoka, K.,Hachiya, A.,Imahashi, M.,Yokomaku, Y.,Watanabe, N.,Iwatani, Y.; Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA.; Nucleic Acids Res., 46:10368-10379, 2018; PubMed: 30060196; DOI: 10.1093/nar/gky676

Experimental method

X-RAY DIFFRACTION (2.2 Å)