5XXY
Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A
Summary for 5XXY
Entry DOI | 10.2210/pdb5xxy/pdb |
Descriptor | heavy chain of atezolizumab fab, light chain of atezolizumab fab, Programmed cell death 1 ligand 1, ... (4 entities in total) |
Functional Keywords | pd-l1, atezolizumab, immune system |
Biological source | Homo sapiens More |
Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7 |
Total number of polymer chains | 3 |
Total formula weight | 63268.73 |
Authors | |
Primary citation | Zhang, F.,Qi, X.,Wang, X.,Wei, D.,Wu, J.,Feng, L.,Cai, H.,Wang, Y.,Zeng, N.,Xu, T.,Zhou, A.,Zheng, Y. Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab. Oncotarget, 8:90215-90224, 2017 Cited by PubMed: 29163822DOI: 10.18632/oncotarget.21652 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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