5XSN

The catalytic domain of GdpP with c-di-AMP

Summary for 5XSN

Entry DOI	10.2210/pdb5xsn/pdb
Descriptor	Phosphodiesterase acting on cyclic dinucleotides, MANGANESE (II) ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ... (4 entities in total)
Functional Keywords	phosphodiesterase, hydrolase
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	77798.89
Authors	Wang, F.,Gu, L. (deposition date: 2017-06-14, release date: 2018-01-31, Last modification date: 2023-11-22)
Primary citation	Wang, F.,He, Q.,Su, K.,Wei, T.,Xu, S.,Gu, L. Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475:191-205, 2018 Cited by PubMed: 29203646 DOI: 10.1042/BCJ20170739 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.501 Å)

Structure validation