5XBT

The structure of BrlR bound to c-di-GMP

Summary for 5XBT

• Entry DOI: 10.2210/pdb5xbt/pdb
• Related: 5XBW
• Descriptor: Probable transcriptional regulator, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GLYCEROL, ... (6 entities in total)
• Functional Keywords: c-di-gmp, receptor, hth domain, dna binding protein
• Biological source: Pseudomonas aeruginosa PAO1
• Total number of polymer chains: 2
• Total formula weight: 66523.76

Authors

Wang, F.,Qing, H.,Gu, L. (deposition date: 2017-03-21, release date: 2018-05-02, Last modification date: 2024-03-27)

• Primary citation: Wang, F.,He, Q.,Yin, J.,Xu, S.,Hu, W.,Gu, L.; BrlR from Pseudomonas aeruginosa is a receptor for both cyclic di-GMP and pyocyanin.; Nat Commun, 9:2563-2563, 2018; PubMed: 29967320; DOI: 10.1038/s41467-018-05004-y

Experimental method

X-RAY DIFFRACTION (2.495 Å)