5X8M
PD-L1 in complex with durvalumab
Summary for 5X8M
Entry DOI | 10.2210/pdb5x8m/pdb |
Related | 5X8L |
Descriptor | Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain, ... (4 entities in total) |
Functional Keywords | complex, antibody, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7 |
Total number of polymer chains | 3 |
Total formula weight | 63229.81 |
Authors | |
Primary citation | Lee, H.T.,Lee, J.Y.,Lim, H.,Lee, S.H.,Moon, Y.J.,Pyo, H.J.,Ryu, S.E.,Shin, W.,Heo, Y.S. Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab Sci Rep, 7:5532-5532, 2017 Cited by PubMed: 28717238DOI: 10.1038/s41598-017-06002-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.661 Å) |
Structure validation
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