5X54
Crystal structure of the Keap1 Kelch domain in complex with a tetrapeptide
Summary for 5X54
Entry DOI | 10.2210/pdb5x54/pdb |
Descriptor | Kelch-like ECH-associated protein 1, ACE-GLU-TRP-TRP-TRP, ACETATE ION, ... (4 entities in total) |
Functional Keywords | transcription, complex, inhibitor, kelch domain, nrf2, oxidative stress, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q14145 |
Total number of polymer chains | 4 |
Total formula weight | 65178.68 |
Authors | Sogabe, S.,Kadotani, A.,Lane, W.,Snell, G. (deposition date: 2017-02-14, release date: 2017-03-29, Last modification date: 2023-11-22) |
Primary citation | Sogabe, S.,Sakamoto, K.,Kamada, Y.,Kadotani, A.,Fukuda, Y.,Sakamoto, J. Discovery of a Kelch-like ECH-associated protein 1-inhibitory tetrapeptide and its structural characterization Biochem. Biophys. Res. Commun., 486:620-625, 2017 Cited by PubMed: 28315327DOI: 10.1016/j.bbrc.2017.03.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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