5WVX

Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza

Summary for 5WVX

Entry DOI	10.2210/pdb5wvx/pdb
Related	1AVA
Descriptor	Trypsin/chymotrypsin inhibitor, 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID (3 entities in total)
Functional Keywords	kunitz type trypsin inhibitor, alpha amylase inhibitor, hydrolase inhibitor
Biological source	Alocasia macrorrhizos (Giant taro)
Total number of polymer chains	2
Total formula weight	40412.94
Authors	Palayam, M.,Radhakrishnan, M.,Lakshminarayanan, K.,Balu, K.E.,Ganapathy, J.,Krishnasamy, G. (deposition date: 2016-12-29, release date: 2018-06-13, Last modification date: 2023-11-22)
Primary citation	Palayam, M.,Ganapathy, J.,Balu, K.E.,Pennathur, G.,Krishnasamy, G. Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition. Int. J. Biol. Macromol., 113:681-691, 2018 Cited by PubMed: 29505868 DOI: 10.1016/j.ijbiomac.2018.03.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.003 Å)

Structure validation