5WUK
Crystal structure of EED [G255D] in complex with EZH2 peptide and EED226 compound
Summary for 5WUK
Entry DOI | 10.2210/pdb5wuk/pdb |
Descriptor | Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, GLYCEROL, ... (5 entities in total) |
Functional Keywords | eed, gene regulation |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: O75530 Q15910 |
Total number of polymer chains | 2 |
Total formula weight | 46353.81 |
Authors | |
Primary citation | Li, L.,Feng, L.,Shi, M.,Zeng, J.,Chen, Z.,Zhong, L.,Huang, L.,Guo, W.,Huang, Y.,Qi, W.,Lu, C.,Li, E.,Zhao, K.,Gu, J. Split luciferase-based biosensors for characterizing EED binders Anal. Biochem., 522:37-45, 2017 Cited by PubMed: 28111304DOI: 10.1016/j.ab.2017.01.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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