5W3Q
L28F E.coli DHFR in complex with NADPH
Summary for 5W3Q
Entry DOI | 10.2210/pdb5w3q/pdb |
Descriptor | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 18838.86 |
Authors | Oyen, D.,Wright, P.E.,Wilson, I.A. (deposition date: 2017-06-08, release date: 2017-08-09, Last modification date: 2023-10-04) |
Primary citation | Oyen, D.,Fenwick, R.B.,Aoto, P.C.,Stanfield, R.L.,Wilson, I.A.,Dyson, H.J.,Wright, P.E. Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion. J. Am. Chem. Soc., 139:11233-11240, 2017 Cited by PubMed: 28737940DOI: 10.1021/jacs.7b05958 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.401 Å) |
Structure validation
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