5W1W

Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex

Summary for 5W1W

• Entry DOI: 10.2210/pdb5w1w/pdb
• Related: 5w1v
• Descriptor: HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, leader peptide of HLA class I histocompatibility antigen, A alpha chain, ... (5 entities in total)
• Functional Keywords: t-cell receptor, tcr, hla-e, cmv, pmhc-tcr complex, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P13747; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 20
• Total formula weight: 381038.03

Authors

Gras, S.,Walpole, N.,Farenc, C.,Rossjohn, J. (deposition date: 2017-06-05, release date: 2017-10-04, Last modification date: 2018-01-03)

• Primary citation: Sullivan, L.C.,Walpole, N.G.,Farenc, C.,Pietra, G.,Sum, M.J.W.,Clements, C.S.,Lee, E.J.,Beddoe, T.,Falco, M.,Mingari, M.C.,Moretta, L.,Gras, S.,Rossjohn, J.,Brooks, A.G.; A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.; J. Biol. Chem., 292:21149-21158, 2017; PubMed: 28972140; DOI: 10.1074/jbc.M117.807719

Experimental method

X-RAY DIFFRACTION (3.1 Å)