5VJK

Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9)

Summary for 5VJK

Entry DOI	10.2210/pdb5vjk/pdb
Related	5VJL 5VJM
Descriptor	Hemagglutinin HA1, Hemagglutinin HA2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	influenza virus, hemagglutinin, mutant, receptor specificity, viral protein
Biological source	Influenza A virus More
Total number of polymer chains	2
Total formula weight	57476.06
Authors	Zhu, X.,Wilson, I.A. (deposition date: 2017-04-19, release date: 2017-05-24, Last modification date: 2023-10-04)
Primary citation	de Vries, R.P.,Peng, W.,Grant, O.C.,Thompson, A.J.,Zhu, X.,Bouwman, K.M.,de la Pena, A.T.T.,van Breemen, M.J.,Ambepitiya Wickramasinghe, I.N.,de Haan, C.A.M.,Yu, W.,McBride, R.,Sanders, R.W.,Woods, R.J.,Verheije, M.H.,Wilson, I.A.,Paulson, J.C. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog., 13:e1006390-e1006390, 2017 Cited by PubMed: 28617868 DOI: 10.1371/journal.ppat.1006390 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.593 Å)

Structure validation