5VEZ
DNA polymerase beta substrate complex with 8-oxoG:A at the primer terminus and incoming dCTP analog
Summary for 5VEZ
Entry DOI | 10.2210/pdb5vez/pdb |
Descriptor | DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total) |
Functional Keywords | transferase ligase / dna, transferase-dna, ligase-dna complex, transferase/dna, ligase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48306.35 |
Authors | Freudenthal, B.D.,Schaich, M.A.,Whitaker, A.M.,Smith, M.R. (deposition date: 2017-04-06, release date: 2017-05-10, Last modification date: 2023-10-04) |
Primary citation | Whitaker, A.M.,Smith, M.R.,Schaich, M.A.,Freudenthal, B.D. Capturing a mammalian DNA polymerase extending from an oxidized nucleotide. Nucleic Acids Res., 45:6934-6944, 2017 Cited by PubMed: 28449123DOI: 10.1093/nar/gkx293 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.039 Å) |
Structure validation
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