5VBL
Structure of apelin receptor in complex with agonist peptide
Summary for 5VBL
Entry DOI | 10.2210/pdb5vbl/pdb |
Descriptor | agonist peptide, Apelin receptor,Rubredoxin,Apelin receptor Chimera, ZINC ION, ... (5 entities in total) |
Functional Keywords | human apelin receptor complex, agonist peptide, amg3054, gpcr, rubredoxin, membrane protein, lcp, synchrotron radiation, peptide-gcpr recognition, cardiovascular drug target, specific recognition, binding specificity, designed agonist peptide mimic, isopeptide |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane : P35414 |
Total number of polymer chains | 2 |
Total formula weight | 49248.92 |
Authors | Ma, Y.,Yue, Y.,Ma, Y.,Zhang, Q.,Zhou, Q.,Song, Y.,Shen, Y.,Li, X.,Ma, X.,Li, C.,Hanson, M.A.,Han, G.W.,Sickmier, E.A.,Swaminath, G.,Zhao, S.,Stevems, R.C.,Hu, L.A.,Zhong, W.,Zhang, M.,Xu, F. (deposition date: 2017-03-29, release date: 2017-05-31, Last modification date: 2023-11-15) |
Primary citation | Ma, Y.,Yue, Y.,Ma, Y.,Zhang, Q.,Zhou, Q.,Song, Y.,Shen, Y.,Li, X.,Ma, X.,Li, C.,Hanson, M.A.,Han, G.W.,Sickmier, E.A.,Swaminath, G.,Zhao, S.,Stevens, R.C.,Hu, L.A.,Zhong, W.,Zhang, M.,Xu, F. Structural Basis for Apelin Control of the Human Apelin Receptor Structure, 25:858-866.e4, 2017 Cited by PubMed: 28528775DOI: 10.1016/j.str.2017.04.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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