5VB9
IL-17A in complex with peptide
Summary for 5VB9
Entry DOI | 10.2210/pdb5vb9/pdb |
Descriptor | Interleukin-17A, Peptide inhibitor, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | il17, inhibitor, immune system - inhibitor complex, immune system / inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: Q16552 |
Total number of polymer chains | 4 |
Total formula weight | 31412.98 |
Authors | Antonysamy, S.,Russell, M.,Zhang, A.,Groshong, C.,Manglicmot, D.,Lu, F.,Benach, J.,Wasserman, S.R.,Zhang, F.,Afshar, S.,Bina, H.,Broughton, H.,Chalmers, M.,Dodge, J.,Espada, A.,Jones, S.,Ting, J.P.,Woodman, M. (deposition date: 2017-03-28, release date: 2018-02-14) |
Primary citation | Ting, J.P.,Tung, F.,Antonysamy, S.,Wasserman, S.,Jones, S.B.,Zhang, F.F.,Espada, A.,Broughton, H.,Chalmers, M.J.,Woodman, M.E.,Bina, H.A.,Dodge, J.A.,Benach, J.,Zhang, A.,Groshong, C.,Manglicmot, D.,Russell, M.,Afshar, S. Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery. PLoS ONE, 13:e0190850-e0190850, 2018 Cited by PubMed: 29329326DOI: 10.1371/journal.pone.0190850 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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