5V5L

Crystal structure of HLA-B*5801 complex with HIV-1 gag derived peptide TW10

Summary for 5V5L

• Entry DOI: 10.2210/pdb5v5l/pdb
• Related: 5V5M
• Descriptor: HLA class I histocompatibility antigen, B-58 alpha chain, Beta-2-microglobulin, TW10, ... (4 entities in total)
• Functional Keywords: hla, hiv, gag, tw10, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P10319; Secreted . Note=(Microbial infection) In the presence of M: P61769
• Total number of polymer chains: 6
• Total formula weight: 90280.14

Authors

Li, X.,Wang, J.-H. (deposition date: 2017-03-14, release date: 2017-06-14, Last modification date: 2023-10-04)

• Primary citation: Li, X.,Lamothe, P.A.,Walker, B.D.,Wang, J.H.; Crystal structure of HLA-B*5801 with a TW10 HIV Gag epitope reveals a novel mode of peptide presentation.; Cell. Mol. Immunol., 14:631-634, 2017; PubMed: 28552904; DOI: 10.1038/cmi.2017.24

Experimental method

X-RAY DIFFRACTION (2.002 Å)