5V4K

Crystal structure of NEDD4 LIR-fused human LC3B_2-119

Summary for 5V4K

• Entry DOI: 10.2210/pdb5v4k/pdb
• Descriptor: Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, GLYCEROL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: autophagy, ubiquitin e3 ligase, hect, lir, lc3, signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytoskeleton: Q9GZQ8
• Total number of polymer chains: 2
• Total formula weight: 31309.42

Authors

Qiu, Y.,Zheng, Y.,Schulman, B. (deposition date: 2017-03-09, release date: 2017-05-17, Last modification date: 2022-04-13)

• Primary citation: Qiu, Y.,Zheng, Y.,Wu, K.P.,Schulman, B.A.; Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4.; Protein Sci., 26:1674-1680, 2017; PubMed: 28470758; DOI: 10.1002/pro.3186

Experimental method

X-RAY DIFFRACTION (2.099 Å)