5UY9

Prolyl isomerase Pin1 R14A mutant bound with Brd4 peptide

Summary for 5UY9

• Entry DOI: 10.2210/pdb5uy9/pdb
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Brd4 peptide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (5 entities in total)
• Functional Keywords: isomerase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q13526
• Total number of polymer chains: 2
• Total formula weight: 19591.56

Authors

Dong, S.-H.,Nair, S. (deposition date: 2017-02-23, release date: 2017-04-26, Last modification date: 2018-01-24)

• Primary citation: Hu, X.,Dong, S.H.,Chen, J.,Zhou, X.Z.,Chen, R.,Nair, S.,Lu, K.P.,Chen, L.F.; Prolyl isomerase PIN1 regulates the stability, transcriptional activity and oncogenic potential of BRD4.; Oncogene, 36:5177-5188, 2017; PubMed: 28481868; DOI: 10.1038/onc.2017.137

Experimental method

X-RAY DIFFRACTION (1.85 Å)