5UUT

N-myristoyltransferase 1 (NMT) bound to myristoyl-CoA

Summary for 5UUT

• Entry DOI: 10.2210/pdb5uut/pdb
• Descriptor: Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: myristoylation, myristoyl-coa, cancer, co/post-translational modification, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 93246.72

Authors

Goodwin, O.,Pegan, S. (deposition date: 2017-02-17, release date: 2018-01-17, Last modification date: 2024-03-06)

• Primary citation: Kim, S.,Alsaidan, O.A.,Goodwin, O.,Li, Q.,Sulejmani, E.,Han, Z.,Bai, A.,Albers, T.,Beharry, Z.,Zheng, Y.G.,Norris, J.S.,Szulc, Z.M.,Bielawska, A.,Lebedyeva, I.,Pegan, S.D.,Cai, H.; Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression.; Cancer Res., 77:6950-6962, 2017; PubMed: 29038344; DOI: 10.1158/0008-5472.CAN-17-0981

Experimental method

X-RAY DIFFRACTION (2.252 Å)