5UTK
Crystal structure of the membrane proximal three fibronectin type III (FNIII) domains of Tie2 (Tie2[FNIIIa-c])
Summary for 5UTK
| Entry DOI | 10.2210/pdb5utk/pdb |
| Descriptor | Angiopoietin-1 receptor (2 entities in total) |
| Functional Keywords | receptor tyrosine kinase, extracellular region, dimerization, fibronectin type iii domain, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 68273.95 |
| Authors | Moore, J.O.,Lemmon, M.A.,Ferguson, K.M. (deposition date: 2017-02-15, release date: 2017-04-12, Last modification date: 2019-12-04) |
| Primary citation | Moore, J.O.,Lemmon, M.A.,Ferguson, K.M. Dimerization of Tie2 mediated by its membrane-proximal FNIII domains. Proc. Natl. Acad. Sci. U.S.A., 114:4382-4387, 2017 Cited by PubMed: 28396397DOI: 10.1073/pnas.1617800114 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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