5URS

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P178

Summary for 5URS

• Entry DOI: 10.2210/pdb5urs/pdb
• Related: 3TSB 3TSD 3USB 4MJM 4MY1 4MY8 4MY9 4MYA 4MYX 4QM1 5urr
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, N-[4-chloro-3-(alpha-D-ribofuranosyloxy)phenyl]-N'-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea, ... (9 entities in total)
• Functional Keywords: impdh, tim barrel, delta cbs, structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase
• Biological source: Bacillus anthracis; More
• Total number of polymer chains: 8
• Total formula weight: 333135.82

Authors

Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-02-12, release date: 2017-03-08, Last modification date: 2023-10-04)

• Primary citation: Kim, Y.,Maltseva, N.,Makowska-Grzyska, M.,Gu, M.,Gollapalli, D.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P178; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.388 Å)