5UR8

Human antibody fragment (Fab) to meningococcal Factor H binding protein

Summary for 5UR8

Entry DOI	10.2210/pdb5ur8/pdb
Descriptor	human immunoglobulin gamma, heavy chain Fd fragment, human immunoglobulin gamma, kappa light chain (3 entities in total)
Functional Keywords	immunoglobulin gamma, fragment antigen binding, fab, factor h binding protein, immune system
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	49131.90
Authors	Beernink, P.T. (deposition date: 2017-02-09, release date: 2018-02-14, Last modification date: 2023-10-04)
Primary citation	Lopez-Sagaseta, J.,Beernink, P.T.,Bianchi, F.,Santini, L.,Frigimelica, E.,Lucas, A.H.,Pizza, M.,Bottomley, M.J. Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. Nat Commun, 9:528-528, 2018 Cited by PubMed: 29410413 DOI: 10.1038/s41467-018-02827-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75500231418 Å)

Structure validation