5UN2
Crystal Structure of Mouse Cadherin-23 EC19-21 with non-syndromic deafness (DFNB12) associated mutation R2029W
Summary for 5UN2
Entry DOI | 10.2210/pdb5un2/pdb |
Descriptor | Cadherin-23, CALCIUM ION, POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | hearing, mechanotransduction, adhesion, calcium-binding protein, cell adhesion |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 37977.59 |
Authors | Jaiganesh, A.,Sotomayor, M. (deposition date: 2017-01-30, release date: 2018-02-07, Last modification date: 2023-10-04) |
Primary citation | Jaiganesh, A.,De-la-Torre, P.,Patel, A.A.,Termine, D.J.,Velez-Cortes, F.,Chen, C.,Sotomayor, M. Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26:1210-, 2018 Cited by PubMed: 30033219DOI: 10.1016/j.str.2018.06.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
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