5U6Y

Pseudo-atomic model of the CaMKIIa holoenzyme.

Summary for 5U6Y

Entry DOI	10.2210/pdb5u6y/pdb
EMDB information	8514
Descriptor	Calcium/calmodulin-dependent protein kinase type II subunit alpha (1 entity in total)
Functional Keywords	calcium/calmodulin-dependent kinase ii (camkii), cell signaling, calcium, calmodulin (cam), long-term potentiation (ltp), long-term depression (ltd), synaptic plasticity, cooperativity, electron microscopy (em), single particle reconstruction, intrinsic disorder, transferase
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	12
Total formula weight	627378.42
Authors	Myers, J.,Reichow, S.L. (deposition date: 2016-12-09, release date: 2017-06-21, Last modification date: 2024-03-13)
Primary citation	Myers, J.B.,Zaegel, V.,Coultrap, S.J.,Miller, A.P.,Bayer, K.U.,Reichow, S.L. The CaMKII holoenzyme structure in activation-competent conformations. Nat Commun, 8:15742-15742, 2017 Cited by PubMed: 28589927 DOI: 10.1038/ncomms15742 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (20 Å)

Structure validation