5U5S
Solution structures of Brd2 second bromodomain in complex with stat3 peptide
Summary for 5U5S
Entry DOI | 10.2210/pdb5u5s/pdb |
NMR Information | BMRB: 30206 |
Descriptor | Bromodomain-containing protein 2, Stat3 peptide (2 entities in total) |
Functional Keywords | brd2, brd4, bromodomain, stat3, th17, p300, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 14697.94 |
Authors | Zeng, L.,Zhou, M.-M. (deposition date: 2016-12-07, release date: 2017-03-22, Last modification date: 2023-11-15) |
Primary citation | Cheung, K.L.,Zhang, F.,Jaganathan, A.,Sharma, R.,Zhang, Q.,Konuma, T.,Shen, T.,Lee, J.Y.,Ren, C.,Chen, C.H.,Lu, G.,Olson, M.R.,Zhang, W.,Kaplan, M.H.,Littman, D.R.,Walsh, M.J.,Xiong, H.,Zeng, L.,Zhou, M.M. Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation. Mol. Cell, 65:1068-1080.e5, 2017 Cited by PubMed: 28262505DOI: 10.1016/j.molcel.2016.12.022 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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