5TSP

Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase (NanI) in complex with a CHES

Summary for 5TSP

Entry DOI	10.2210/pdb5tsp/pdb
Descriptor	Sialidase, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, ... (4 entities in total)
Functional Keywords	neuraminidase, hydrolase
Biological source	Clostridium perfringens ATCC 13124
Total number of polymer chains	2
Total formula weight	103715.10
Authors	Lee, Y.,Youn, H.-S.,Lee, J.-G.,An, J.Y.,Park, K.R.,Kang, J.Y.,Jin, M.S.,Ryu, Y.B.,Park, K.H.,Eom, S.H. (deposition date: 2016-10-31, release date: 2017-03-29, Last modification date: 2023-11-08)
Primary citation	Lee, Y.,Youn, H.-S.,Lee, J.-G.,An, J.Y.,Park, K.R.,Kang, J.Y.,Ryu, Y.B.,Jin, M.S.,Park, K.H.,Eom, S.H. Crystal structure of the catalytic domain of Clostridium perfringens neuraminidase in complex with a non-carbohydrate-based inhibitor, 2-(cyclohexylamino)ethanesulfonic acid Biochem. Biophys. Res. Commun., 486:470-475, 2017 Cited by PubMed: 28315686 DOI: 10.1016/j.bbrc.2017.03.064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation