5TR8

Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6.

Summary for 5TR8

• Entry DOI: 10.2210/pdb5tr8/pdb
• Descriptor: 441D6 Fab Light chain, 441D6 Fab Heavy chain, NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: nanoparticle, ferritin, immune system, antibody
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47691.37

Authors

Joyce, M.G.,Kanekiyo, M.,Mascola, J.R.,Graham, B.S.,Kwong, P.D. (deposition date: 2016-10-25, release date: 2018-05-09, Last modification date: 2023-10-04)

• Primary citation: Kanekiyo, M.,Joyce, M.G.,Gillespie, R.A.,Gallagher, J.R.,Andrews, S.F.,Yassine, H.M.,Wheatley, A.K.,Fisher, B.E.,Ambrozak, D.R.,Creanga, A.,Leung, K.,Yang, E.S.,Boyoglu-Barnum, S.,Georgiev, I.S.,Tsybovsky, Y.,Prabhakaran, M.S.,Andersen, H.,Kong, W.P.,Baxa, U.,Zephir, K.L.,Ledgerwood, J.E.,Koup, R.A.,Kwong, P.D.,Harris, A.K.,McDermott, A.B.,Mascola, J.R.,Graham, B.S.; Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.; Nat.Immunol., 20:362-372, 2019; PubMed: 30742080; DOI: 10.1038/s41590-018-0305-x

Experimental method

X-RAY DIFFRACTION (2.01 Å)