5TQS
Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2
Summary for 5TQS
Entry DOI | 10.2210/pdb5tqs/pdb |
Related | 5TQ1 |
Descriptor | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, Receptor protein-tyrosine kinase (3 entities in total) |
Functional Keywords | sh2, phospholipase, phosphopeptide, hydrolase |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 8 |
Total formula weight | 53980.48 |
Authors | Wuttke, D.S.,McKercher, M.A. (deposition date: 2016-10-24, release date: 2017-04-19, Last modification date: 2023-11-15) |
Primary citation | McKercher, M.A.,Guan, X.,Tan, Z.,Wuttke, D.S. Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-gamma 1 Protein. Biochemistry, 56:2225-2237, 2017 Cited by PubMed: 28376302DOI: 10.1021/acs.biochem.7b00023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.876 Å) |
Structure validation
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