5TP3

Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4

Summary for 5TP3

• Entry DOI: 10.2210/pdb5tp3/pdb
• Descriptor: F-VHH-4 (2 entities in total)
• Functional Keywords: nanobody, respiratory syncytial virus, ig fold, fusion glycoprotein, pseudomerohedral, immune system
• Biological source: Lama glama (llama)
• Total number of polymer chains: 2
• Total formula weight: 27216.16

Authors

Wrapp, D.,Gilman, M.S.A.,McLellan, J.S. (deposition date: 2016-10-19, release date: 2017-02-22, Last modification date: 2023-10-04)

• Primary citation: Rossey, I.,Gilman, M.S.,Kabeche, S.C.,Sedeyn, K.,Wrapp, D.,Kanekiyo, M.,Chen, M.,Mas, V.,Spitaels, J.,Melero, J.A.,Graham, B.S.,Schepens, B.,McLellan, J.S.,Saelens, X.; Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.; Nat Commun, 8:14158-14158, 2017; PubMed: 28194013; DOI: 10.1038/ncomms14158

Experimental method

X-RAY DIFFRACTION (1.874 Å)