5THV

Crystal Structure of G305A HDAC8 in complex with M344

Summary for 5THV

Entry DOI	10.2210/pdb5thv/pdb
Related	5THS 5THT 5THU
Descriptor	Histone deacetylase 8, ZINC ION, POTASSIUM ION, ... (6 entities in total)
Functional Keywords	zinc histone deactylase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	89007.79
Authors	Porter, N.J.,Christianson, D.W. (deposition date: 2016-09-30, release date: 2016-12-21, Last modification date: 2023-10-04)
Primary citation	Porter, N.J.,Christianson, N.H.,Decroos, C.,Christianson, D.W. Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. Biochemistry, 55:6718-6729, 2016 Cited by PubMed: 27933794 DOI: 10.1021/acs.biochem.6b01014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.868 Å)

Structure validation