5T1M

Cetuximab Fab in complex with CQYDLSTRRLKC

Summary for 5T1M

• Entry DOI: 10.2210/pdb5t1m/pdb
• Related: 4GW1 4IWE 5ETU 5EUK 5F88 5FF6 5I2I 5IOP 5IR1 5ITF 5IV2 5IVZ 5T1K 5T1L 5TH2
• Descriptor: CETUXIMAB FAB LIGHT CHAIN, CETUXIMAB FAB HEAVY CHAIN, CYCLIC PEPTIDE CQYDLSTRRLKC, ... (6 entities in total)
• Functional Keywords: antibody, anti-egfr, immune system
• Biological source: Mus musculus, Homo sapiens; More
• Total number of polymer chains: 7
• Total formula weight: 99470.87

Authors

Bzymek, K.P.,Williams, J.C. (deposition date: 2016-08-19, release date: 2016-10-26, Last modification date: 2023-10-04)

• Primary citation: Bzymek, K.P.,Avery, K.A.,Ma, Y.,Horne, D.A.,Williams, J.C.; Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.; Acta Crystallogr F Struct Biol Commun, 72:820-830, 2016; PubMed: 27834791; DOI: 10.1107/S2053230X16016149

Experimental method

X-RAY DIFFRACTION (2.53 Å)