5T1J
Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet
Summary for 5T1J
Entry DOI | 10.2210/pdb5t1j/pdb |
Descriptor | T-box transcription factor TBX21, DNA (2 entities in total) |
Functional Keywords | t-bet, tbox, tbx21, dna looping, transcriptional regulation, master regulator, transcription factor, dna binding, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus: Q9JKD8 |
Total number of polymer chains | 6 |
Total formula weight | 76372.23 |
Authors | Liu, C.F.,Brandt, G.S.,Hoang, Q.,Hwang, E.S.,Naumova, N.,Lazarevic, V.,Dekker, J.,Glimcher, L.H.,Ringe, D.,Petsko, G.A. (deposition date: 2016-08-19, release date: 2016-10-26, Last modification date: 2023-12-27) |
Primary citation | Liu, C.F.,Brandt, G.S.,Hoang, Q.Q.,Naumova, N.,Lazarevic, V.,Hwang, E.S.,Dekker, J.,Glimcher, L.H.,Ringe, D.,Petsko, G.A. Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proc.Natl.Acad.Sci.USA, 113:E6572-E6581, 2016 Cited by PubMed: 27791029DOI: 10.1073/pnas.1613914113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.947 Å) |
Structure validation
Download full validation report