5SZX
Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA
Summary for 5SZX
Entry DOI | 10.2210/pdb5szx/pdb |
Related | 5T01 |
Descriptor | DNA (5'-D(*TP*CP*TP*TP*CP*AP*TP*(5CM)P*GP*CP*TP*CP*AP*GP*TP*GP*CP*T)-3'), DNA (5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*GP*(5CM)P*GP*AP*TP*GP*AP*AP*G)-3'), Zta transcription factor, ... (5 entities in total) |
Functional Keywords | zta, zebra, bzlf-1, ap-1, epstein-barr virus, ebv, 5-methylcytosine, 5mc, dna methylation, transcription factor, basic leucine-zipper, bzip, transcription regulator-dna complex, transcription regulator/dna |
Biological source | Epstein-Barr virus (HHV-4, Human herpesvirus 4) More |
Total number of polymer chains | 4 |
Total formula weight | 25752.29 |
Authors | Hong, S.,Horton, J.R.,Cheng, X. (deposition date: 2016-08-15, release date: 2017-03-01, Last modification date: 2023-10-04) |
Primary citation | Hong, S.,Wang, D.,Horton, J.R.,Zhang, X.,Speck, S.H.,Blumenthal, R.M.,Cheng, X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res., 45:2503-2515, 2017 Cited by PubMed: 28158710DOI: 10.1093/nar/gkx057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.251 Å) |
Structure validation
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